Dextran Sulfate Sodium 10

€430,00 EUR

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Specification Safety Data Sheet

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Contact Information:
Email: order.maglebiopolymers@maglegroup.com
Phone: +46 40 38 33 00
Address: Københavnsvej 140
4600 Køge
Denmark

Dextran Sulfate Sodium 10 Grade refers to the sodium salt of sulfated dextran with a low average molecular weight at approximately 10,000 Da. It is a polyanionic derivative of dextran, produced by esterification of dextran resulting in 16-19 % sulfur content.

Dextran Sulfate Sodium 10 appears as a white to very slightly yellow powder that is highly soluble in water. It is known for its strong negative charge density and is often used in topical formulations due to its anti-inflammatory and anti-edema characteristics.

Biotechnology: Used in cell culture media as an additive to prevent aggregation of particles or cells and also to stabilize growth factors by preventing their adsorption to surfaces.
Research: Dextran Sulfate Sodium 10 can be used as a gentle precipitation agent for protein purification.
Drug delivery formulations: Can be complexed with polycations to produce nanogels for drug delivery.

Negative charge:Highly negatively charged Dextran Sulfate Sodium Standard strongly binds positively charged molecules and ions.
Biotechnology: Used in cell culture media as an additive to prevent aggregation of particles or cells and also to stabilize growth factors by preventing their adsorption to surfaces.

Research: Dextran Sulfate Sodium 10 can be used as a gentle precipitation agent for protein purification.

Drug delivery formulations: Can be complexed with polycations to produce nanogels for drug delivery.

Negative charge:Highly negatively charged Dextran Sulfate Sodium Standard strongly binds positively charged molecules and ions.

Common Applications

Biotechnology: Used in cell culture media as an additive to prevent aggregation of particles or cells and also to stabilize growth factors by preventing their adsorption to surfaces.
Research: Dextran Sulfate Sodium 10 can be used as a gentle precipitation agent for protein purification.
Drug delivery formulations: Can be complexed with polycations to produce nanogels for drug delivery.

Research: Dextran Sulfate Sodium 10 can be used as a gentle precipitation agent for protein purification.

Drug delivery formulations: Can be complexed with polycations to produce nanogels for drug delivery.

Negative charge:Highly negatively charged Dextran Sulfate Sodium Standard strongly binds positively charged molecules and ions.

Handling & Compatibility

Handling: Hygroscopic and clumpy if exposed to moisture, cap the bottle tightly. Weigh quickly or in a low-humidity environment. The fine powder can be electrostatic; anti-static measures or dissolving in a weighed container is helpful.
Compatibility: Forms precipitates with polycations and will also precipitate in presence of high concentrations of bivalent cations.

Key Properties

Solubility: Freely soluble in water and salt solutions; for example, up to 20–30% w/v in water yields a clear, slightly viscous solution.
Reactivity: Forms insoluble complexes with polycations like DEAE-dextran and can also chelate cationic proteins.
Viscosity: Low – a 10% solution is only mildly viscous, similar to 10% dextran of same size.
Stability: Dry powder is stable for years if kept dry.
Available in smaller packs (100 and 500g) and bulk quantities (> 5kg).

Additional Features

Low bioburden.
Meets residual solvent criteria.
Kosher and allergen-free status usually available due to non-animal, fermentation origin.